Autoimmune and Immunodeficiences:
Primary immune deficiency (PID): Genetic condition that prevents the body’s immune system from functioning properly. Over 400 types are estimated with many treated by intravenous immunoglobulin (IVIG) therapy.
Chronic inflammatory demyelinating polyneuropathy (CIDP), or Guillain-Barre syndrome: Rare disorder in which your body’s immune system attacks your nerves.
Idiopathic thrombocytopenic purpura (ITP), or thrombocytopenia: Autoimmune disorder that results in low blood platelets, the cells essential for blood clotting.
Kawasaki disease: Disorder affecting children that causes swelling in blood vessels, especially coronary arteries.
Rh incompatibility: Condition during pregnancy where the mother’s blood type is Rh-negative and fetus is Rh-positive and sometimes requires IVIG therapy.
Blood Disorders:
Hemophilia A: Inherited bleeding disorder caused by lack of clotting Factor VIII.
Hemophilia B: Inherited bleeding disorder caused by lack of clotting Factor IX.
Von Willebrand disease (VWD): Most common bleeding disorder where a person is missing or has low amounts of clotting protein von Willebrand factor.
Alpha-1, antitrypsin deficiency: Hereditary disorder that results in low levels of AAT in the blood which can result in life-threatening lung and liver disease.
Thalassemia: Inherited blood disorder that causes your body to have less hemoglobin than normal.
Aplastic anemia: Rare but serious blood condition where bone marrow cannot make enough blood cells for your body to function normally.
Factor I (fibrinogen) deficiency: Inherited bleeding disorder missing fibrinogen which helps platelets “stick together” after injury
Factor II (prothrombin) deficiency: Inherited bleeding disorder where prothrombin, precursor to thrombin, is absent or malfunctioning.
Anti-Thrombin III deficiency, or thrombophilia: Inherited or acquired bleeding disorder whose lack causes higher than normal clot formations.
Factor V (proaccelerin) deficiency, also known as parahemophilia: Inherited bleeding disorder where protein catalyst FV is lacking, impacting the initial phase of the clotting process.
Factor VII (proconvertin) deficiency: Most common of the rare bleeding disorders where lack of FVII, which initiates clotting cascade, causes disruptions in clot formations.
Factor X (Stuart-Prower factor) deficiency: Inherited bleeding disorder with lack of Factor X protein which helps activate enzymes that help form a clot.
Factor XI deficiency, also known as hemophilia C: Inherited bleeding disorder with lack of Factor XI, which helps generate thrombin and leads to a clot within the factor cascade.
Factor XIII deficiency: The rarest factor deficiency disorder which lacks FXIII, which stabilizes the formation of clots.
To find a plasma donation center in your area, click the button below to visit donatingplasma.org.
Red Cross. “What is Plasma in Blood?” 1 June 2022. https://www.redcrossblood.org/donate-blood/dlp/plasma-information.html
CDC. qtd. in: “Animal Bite Accident Statistics.” LegalMatch.com. 1 June 2022. https://www.legalmatch.com/law-library/article/animal-bite-accident-statistics.html
